Fig. 5
From: S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis
S100a4 knockout impairs metastasis. a Gene and protein structure of S100a4 in the mouse. b RNA-seq data confirming S100a4 knockout. c Proliferation of the knockout lines. d Kaplan–Meier plot depicting survival of experimental metastatic assay. Cell line established from the primary tumor in the Pik3caH1047R;Trp53R270H;MMTV-Cre double mutant mice with lung metastasis was used to generate the knockout lines