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Table 5 Incidence rates (IRs, per 1000 person-months) and incidence rate ratios (IRRs) of psychiatric disorders and cardiovascular diseases during the 6 weeks before diagnosis, among women that had a breast diagnostic workup during 2009–2014 in Skåne, Sweden, analysis according to reason for diagnostic workup

From: Psychiatric disorders and cardiovascular diseases during the diagnostic workup of potential breast cancer: a population-based cohort study in Skåne, Sweden

 

No. of events

Crude IR

IRR (95% CI)

Psychiatric disorder

 Reference group*

679,051

20.8

1.0

Due to screening

 Unspecified lump in breast

27

27.7

1.2 (0.8–1.8)

 Benign tumor

31

23.5

1.2 (0.8–1.7)

 Breast cancer

69

20.6

1.0 (0.8–1.3)

Due to symptom

 Unspecified lump in breast

413

29.9

1.1 (1.0–1.3)

 Benign tumor

78

31.7

1.3 (1.0–1.6)

 Breast cancer

139

35.8

1.7 (1.4–2.0)

Cardiovascular disease

 Reference group*

740,161

22.7

1.0

Due to screening

 Unspecified lump in breast

22

22.6

1.3 (0.9–1.9)

 Benign tumor

38

28.8

1.4 (1.1–2.0)

 Breast cancer

131

39.1

1.3 (1.1–1.6)

Due to symptom

 Unspecified lump in breast

181

13.1

1.0 (0.9–1.1)

 Benign tumor

44

17.9

1.2 (0.9–1.6)

 Breast cancer

439

113.2

2.3 (2.1–2.5)

  1. IR incidence rate, IRR incidence rate ratio
  2. *Reference group included person-time accumulated from women who did not have any breast diagnostic workup during the follow-up and the person-time accumulated before the start of workup from women with a breast diagnostic workup during the follow-up
  3. CI confidence interval. IRRs were estimated using Poisson regression, by using attained age as the underlying timescale and adjusting for cohabitation status, registered parish as a proxy for socioeconomic status, and preexisting psychiatric disorders (for outcome of psychiatric disorders) or preexisting cardiovascular diseases (for outcome of cardiovascular diseases)