Table 2 Characteristics of the PredicinePLUS™ platform and detected alterations
Cohort | |
Total cases | 49 |
Cases included in final analyses | 40 |
Regions analyzed | 180 genes |
Panel size | 565 kb |
Samples with detectable alterations | 40/43 (93%) |
Number of genomic alterations | |
Mean | 6.7 |
Median | 6.0 |
Range | 1–22 |
Number of genes with detected alterations | 57 |
Variant allele frequency of detected alterations | 0.11–68.6% |
Commonly detected SNV/indels | TP53, PTEN, PIK3CA, ATM, ESR1 |
Commonly detected copy number amplifications | MYC, CCND1, PIK3CA |
Commonly detected copy number losses | BRCA1, CDKN2A, ATM |