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Fig. 2 | Breast Cancer Research

Fig. 2

From: Association of a novel circulating tumor DNA next-generating sequencing platform with circulating tumor cells (CTCs) and CTC clusters in metastatic breast cancer

Fig. 2

Genomic alterations associated with CTCs. Genomic alterations in ESR1, GATA3, CCND1, and CDH1 were significantly associated with higher number of CTCs (P < 0.05, Mann-Whitney U test). In contrast, alterations in CDKN2A were more commonly observed in samples with low CTC count (P < 0.05, Mann-Whitney U test). In the validation cohort, significant associations were confirmed for ESR1 (P < 0.005) and GATA3 (P < 0.05)

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Breast Cancer Research

ISSN: 1465-542X

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