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Fig. 7 | Breast Cancer Research

Fig. 7

From: Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells

Fig. 7

HEXIM1 and KDOAM25 induced increased sensitivity to doxorubicin. a TNBC lines were treated with vehicle, KDOAM25, and/or doxorubicin (at indicated concentrations) for 18 h and processed for western blot analyses of indicated proteins. b TNBC lines were treated with doxorubicin ± KDOAM25 for 6 days then processed for MTT assays to assess proliferation. *P < 0.01 relative to DMSO-treated cells of the same cell line based on t test. Figures are representative of at least three experiments

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