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Fig. 5 | Breast Cancer Research

Fig. 5

From: Estrogen receptor coregulator binding modulator (ERX-11) enhances the activity of CDK4/6 inhibitors against estrogen receptor-positive breast cancers

Fig. 5

ERX-11+palbociclib treatment alters ER interactions with coregulators. a–d MCF-7 cells were treated with E2 (10−8 M) in the presence or absence of ERX-11 (10 μM), palbociclib (0.25 μM), or ERX-11+palbociclib for 2 h. Cell lysates from treated cells were subjected to immunoprecipitation with ERα antibody. The immunoprecipitates were analyzed by mass spectrometry

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