Table 2 Frequency of nonsynonymous TP53 mutations by tumor subtypes in the Hong Kong breast cancer study (HKBC) and TCGA white population
From: Immune gene expression profiling reveals heterogeneity in luminal breast tumors
| Â | Low-TIL, N (%) | High-ISG, N (%) | High-TIL, N (%) | HER2+basal, N (%) | |
|---|---|---|---|---|---|
HKBC | WT | 29 (100.0%) | 11 (57.9%) | 11 (100.0%) | 10 (45.5%) |
MUT | 0 (0%) | 8 (42.1%) | 0 (0%) | 12 (54.5%) | |
P value* | Ref | 0.0002 | – | < 0.0001 | |
TCGA White | WT | 169 (95.5%) | 142 (87.1%) | 83 (91.2%) | 105 (50.7%) |
MUT | 8 (4.5%) | 21 (12.9%) | 8 (8.8%) | 102 (49.3%) | |
P value* | Ref | 0.01 | 0.18 | < 0.0001 | |