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Fig. 2 | Breast Cancer Research

Fig. 2

From: The atypical cyclin-like protein Spy1 overrides p53-mediated tumour suppression and promotes susceptibility to breast tumourigenesis

Fig. 2

Spy1 overexpression leads to increased mammary tumour susceptibility. a Schematic of DMBA treatment. b Graphical representation of timing of tumour onset (n = 20). c Graphical representation of percentage of mice with tumours (n = 20). d Representative images of tumour pathology from DMBA-induced mammary tumours (i), adenosquamous carcinoma, (ii) and adenomyoepithelioma (iii). Scale bar = 300 μm. e Graphical representation of the number of mice with malignant mammary tumours (n = 20). Mann-Whitney *p < 0.05, **p < 0.001

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