Table 2 Frequencies of metastatic sites, divided by molecular subtype (n = 744)
HR+/HER2− (n = 340) | HR+/HER2+ (n = 131) | HR−/HER2+ (n = 148) | HR−/HER2− (n = 125) | p value | |
|---|---|---|---|---|---|
Type of metastasis per subtype | |||||
Multiple sites | 173 (50.9) | 77 (58.8) | 74 (50.0) | 67 (53.6) | 0.414 |
Only one site | 167 (49.1) | 54 (41.2) | 74 (50.0) | 58 (46.4) | |
Bone | 102 (30.0) | 30 (22.9) | 24 (16.2) | 21 (16.8) | < 0.001 |
Lung | 17 (5.0) | 2 (1.5) | 8 (5.4) | 12 (9.6) | |
Liver | 12 (3.5) | 8 (6.1) | 20 (13.5) | 8 (6.4) | |
Other# | 36 (10.6) | 14 (10.7) | 22 (14.9) | 17 (13.6) | |
All found metastases$ | |||||
Bones | 243 (71.5) | 90 (68.7) | 75 (50.7) | 52 (41.6) | < 0.001 |
Lung | 102 (30.0) | 41 (31.3) | 35 (23.7) | 51 (40.8) | 0.023 |
Liver | 75 (22.1) | 43 (32.8) | 61 (41.2) | 39 (31.2) | < 0.001 |
Brain | 7 (2.1) | 5 (3.8) | 3 (2.0) | 3 (2.4) | 0.713 |
Other/unknown | 35 (10.3) | 13 (9.9) | 21 (14.2) | 17 (13.6) | 0.496 |