Tumour heterogeneity revealed by unsupervised decomposition of dynamic contrast-enhanced magnetic resonance imaging is associated with underlying gene expression patterns and poor survival in breast cancer patients

Table 5 Pathway analysis for the tan module

Category	p value	Corrected p value
Ras signalling pathway	< 10⁻⁴	0.0044
Hedgehog signalling pathway	< 10⁻⁴	0.0044
Apoptosis	0.0003	0.0165
PI3K-Akt signalling pathway	0.0005	0.0215
Longevity regulating pathway	0.0006	0.0219
Notch signalling pathway	0.0011	0.0317
MicroRNAs in cancer	0.0014	0.0343
Spliceosome	0.0022	0.0487
Alzheimer’s disease	0.0049	0.0833
Fatty acid elongation	0.0051	0.0833

ISSN: 1465-542X