Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 3 Image features for survival analysis in the reproducibility cohort

From: Tumour heterogeneity revealed by unsupervised decomposition of dynamic contrast-enhanced magnetic resonance imaging is associated with underlying gene expression patterns and poor survival in breast cancer patients

Feature Recurrence-free survival Overall survival
HR (95% CI) p FDR HR (95% CI) p FDR
Volume 1.5 (1.2–1.8) < 10−3 0.003 1.6 (1.3–2) < 10−4 < 10−3
Maximum probability 1.3 (1.1–1.6) 0.012 0.042 1.4 (1.1–1.7) 0.001 0.006
Median 0.98 (0.73–1.3) 0.890 0.890 0.89 (0.56–1.4) 0.630 0.969
Median 1 (0.78–1.4) 0.840 0.890 0.97 (0.67–1.4) 0.890 0.969
Compactness 1.5 (1.2–1.9) 0.002 0.011 1.7 (1.3–2.2) < 10−4 < 10−3
Energy 1.3 (1.1–1.5) 0.012 0.042 1.3 (1.1–1.6) 0.003 0.009
Skewness 1.1 (0.81–1.4) 0.580 0.677 1.3 (0.92–1.8) 0.150 0.300
Correlation 1.2 (0.87–1.6) 0.290 0.543 1.1 (0.75–1.5) 0.690 0.969
Correlation 1.2 (0.89–1.7) 0.210 0.490 1.4 (0.91–2) 0.130 0.300
Maximum probability 0.9 (0.65–1.2) 0.520 0.662 1 (0.71–1.4) 0.980 0.980
 Kurtosis 0.87 (0.59–1.3) 0.490 0.662 0.98 (0.67–1.4) 0.900 0.969
 Energy 0.84 (0.57–1.2) 0.380 0.591 0.95 (0.65–1.4) 0.780 0.969
 Kurtosis 1.2 (1–1.5) 0.031 0.087 1.3 (1.1–1.5) 0.010 0.028
 Skewness 0.84 (0.6–1.2) 0.310 0.543 1 (0.73–1.4) 0.890 0.969
  1. p values were adjusted by the Benjamini-Hochberg method
  2. The image features that are significantly associated with RFS and OS are shown in italics
  3. HR hazard ratio, CI confidence intervals
  4. Precontrast series (S-0)
  5. Subtraction between the early postcontrast and precontrast series (S-1)