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Table 2 Image features for survival analysis

From: Tumour heterogeneity revealed by unsupervised decomposition of dynamic contrast-enhanced magnetic resonance imaging is associated with underlying gene expression patterns and poor survival in breast cancer patients

Feature Beta HR (95% CI) Wald test p value Corrected p
Volume 0.47 1.6 (1.2–2.2) 8.4 0.004 0.024
Maximum probability 0.46 1.6 (1.1–2.2) 7.9 0.005 0.024
Median 0.44 1.6 (1.1–2.1) 7.6 0.006 0.024
Median 0.44 1.6 (1.1–2.1) 7.3 0.007 0.024
Compactness 0.43 1.5 (1.1–2.2) 6.4 0.011 0.031
Energy 0.34 1.4 (1.0–1.9) 5.2 0.023 0.054
Skewness − 0.56 0.57 (0.3–1.1) 2.9 0.087 0.170
Correlation 0.25 1.3 (0.85–1.9) 1.4 0.230 0.400
Correlation 0.24 1.3 (0.79–2.0) 1.0 0.320 0.500
Maximum probability − 0.11 0.9 (0.57–1.4) 0.20 0.650 0.820
Kurtosis 0.086 1.1 (0.72–1.7) 0.16 0.690 0.820
Energy 0.073 1.1 (0.75–1.6) 0.15 0.700 0.820
Kurtosis 0.047 1.0 (0.76–1.4) 0.08 0.770 0.830
Skewness − 0.014 0.99 (0.67–1.4) 0 0.940 0.940
  1. p values were adjusted by the Benjamini-Hochberg method
  2. HR hazard ratio, CI confidence intervals
  3. Precontrast series (S-0)
  4. Subtraction between the early postcontrast and precontrast series (S-1)