Fig. 3

Example of CAM applied to a a breast image. b Segmented tumour image. c The tumour is decomposed into three regions, and images of the associated regions represent plasma input, fast-flow kinetics and slow-flow kinetics. d Image pixels are grouped into clusters using an affinity propagation clustering method. The clusters represented by the vertices are identified by CAM. e Dynamic enhancement curves for the tumour and the three tumour subregions representing tissue-specific compartments, in which the blue, red and green colours represent the plasma input, fast-flow kinetics and slow-flow kinetics, respectively