Table 2 Median (interquartile range) changes in volumetric density measures by breast side and differences between sides, cases, and controls, overall and stratified on BI-RADS density
| Â | Cases | Controls | ||||||
|---|---|---|---|---|---|---|---|---|
Ipsilateral change* | Contralateral change* | Difference | p value | Ipsilateral change* | Contralateral change* | Difference | p value | |
Overall (n = 1160 cases/2360 controls) | ||||||||
 VPD (%) | − 0.26 (− 1.34, 0.70) | − 0.39 (− 1.39, 0.39) | 0.13 (− 0.69, 1.06) | < .001 | − 0.29 (− 1.26, 0.48) | − 0.28 (− 1.35, 0.50) | − 0.02 (− 0.72, 0.79) | 0.92 |
 DV (cm3) | − 2.10 (− 9.65, 5.06) | − 2.74 (− 10.25, 3.34) | 0.63 (− 6.14, 8.80) | 0.002 | − 1.82 (− 8.09, 3.60) | − 1.89 (− 8.49, 3.84) | 0.05 (− 5.75, 6.07) | 0.77 |
Non-dense (n = 540 cases/1436 controls) | ||||||||
 VPD (%) | − 0.11 (− 0.76, 0.66) | − 0.23 (− 0.86, 0.33) | 0.11 (− 0.49, 0.83) | < .001 | − 0.21 (− 0.85, 0.43) | − 0.18 (− 0.89, 0.40) | − 0.02 (− 0.60, 0.66) | 0.93 |
 DV (cm3) | − 1.28 (− 7.21, 4.98) | − 1.73 (− 8.13, 3.17) | 0.63 (− 4.88, 8.80) | 0.002 | − 1.66 (− 7.01, 3.09) | − 1.58 (− 7.36, 3.17) | 0.09 (− 5.59, 5.69) | 0.89 |
Dense breast (n = 480 cases/822 controls) | ||||||||
 VPD (%) | − 0.65 (− 2.49, 0.82) | − 0.91 (− 2.52, 0.56) | 0.21 (− 1.01, 1.28) | 0.11 | − 0.65 (− 2.33, 0.81) | − 0.79 (− 2.33, 0.82) | 0.00 (− 1.15, 1.13) | 0.97 |
 DV (cm3) | − 3.42 (− 13.23, 4.34) | − 4.30 (− 13.59, 3.33) | 0.61 (− 7.62, 8.35) | 0.38 | − 2.53 (− 10.01, 4.77) | − 2.72 (− 10.93, 5.12) | − 0.02 (− 6.16, 6.83) | 0.77 |