Fig. 2From: Li-Fraumeni syndrome: not a straightforward diagnosis anymore—the interpretation of pathogenic variants of low allele frequency and the differences between germline PVs, mosaicism, and clonal hematopoiesisRecommended workup for a pathogenic or likely pathogenic variant (PV) with low minor allele frequency (MAF) in TP53. a Workup to distinguish somatic mosaicism from clonal hematopoiesis (CH). b Interpretation of genetic testing results in relativesBack to article page