|
DTI variable
|
Pathology status
|
Univariate model
|
Multivariate model*
|
|---|
|
Malignant
|
Benign
|
|---|
|
No.
|
Mean ± SD
|
No.
|
Mean ± SD
|
OR
|
(95% CI)
|
p value
|
OR
|
(95% CI)
|
p value
|
|---|
|
ADC, 10−3 mm2/s
|
|
Mass
|
54
|
1.19 ± 0.27
|
81
|
1.59 ± 0.30
|
0.19
|
(0.10–0.36)
|
< 0.001
|
0.23
|
(0.13–0.43)
|
< 0.001
|
|
Non-mass
|
41
|
1.35 ± 0.36
|
62
|
1.49 ± 0.30
|
0.64
|
(0.40–1.02)
|
0.060
|
0.42
|
(0.22–0.84)
|
0.013
|
| | | | | |
(p = 0.002†)
| | |
(p = 0.20†)
| | |
|
FA
|
|
Mass
|
54
|
0.31 ± 0.17
|
81
|
0.21 ± 0.12
|
2.02
|
(1.36–3.01)
|
< 0.001
|
1.62
|
(0.97–2.71)
|
0.067
|
|
Non-mass
|
41
|
0.24 ± 0.11
|
62
|
0.26 ± 0.14
|
0.94
|
(0.64–1.38)
|
0.74
|
0.54
|
(0.29–1.01)
|
0.053
|
| | | | | |
(p = 0.006†)
| | |
(p = 0.009†)
| | |
- *The multivariate model included ADC, FA, mass vs. non-mass type, log(lesion size), and interactions between mass/non-mass and ADC and FA; ORs were scaled to show change per 1-SD increase in the corresponding variable; FA was log-transformed prior to inclusion in the logistic regression model to reduce right-skewness
- †Wald test comparing the ORs corresponding to masses and non-masses
