|
Clinical/DCE-MRI parameters
|
|
Age, years
|
54.7 ± 11.3
|
49.3 ± 11.8
|
0.63
|
(0.56–0.71)
|
1.60
|
(1.19, 2.16)
|
0.002
|
|
Post-menopausal
|
61 (64.2)
|
67 (46.9)
|
0.59
|
(0.52–0.66)
|
2.04
|
(1.14, 3.62)
|
0.016
|
|
MRI indication: known cancer
|
77 (81.1)
|
84 (58.7)
|
0.61
|
(0.55–0.67)
|
3.00
|
(1.54, 5.85)
|
0.001
|
|
Dense breasts
|
57 (60.0)
|
117 (81.8)
|
0.61
|
(0.55–0.67)
|
0.33
|
(0.18, 0.62)
|
0.001
|
|
BPE category (1–4)
|
1.9 ± 1.0
|
2.3 ± 0.9
|
0.62
|
(0.54–0.70)
|
0.65
|
(0.47, 0.88)
|
0.006
|
|
Lesion size, cm‡
|
26.9 ± 27.1
|
16.3 ± 17.7
|
0.64
|
(0.57–0.71)
|
1.66
|
(1.27, 2.16)
|
< 0.001
|
|
Mass vs. NMLE/focus
|
54 (56.8)
|
81 (56.6)
|
0.50
|
(0.43–0.57)
|
1.01
|
(0.58, 1.76)
|
0.98
|
|
Washout on delayed phase kinetics
|
87 (91.6)
|
111 (77.6)
|
0.57
|
(0.53–0.61)
|
3.14
|
(1.41, 7.00)
|
0.005
|
|
BI-RADS 5 vs. 4
|
17 (17.9)
|
3 (2.1)
|
0.58
|
(0.53–0.62)
|
10.17
|
(2.11, 49.10)
|
0.004
|
|
DTI parameters
|
|
Mean ADC, 10−3 mm2/s
|
1.26 ± 0.32
|
1.55 ± 0.30
|
0.75
|
(0.68–0.82)
|
0.37
|
(0.25, 0.54)
|
< 0.001
|
|
Mean axial diffusivity, 10−3 mm2/s
|
1.62 ± 0.41
|
1.91 ± 0.36
|
0.73
|
(0.66–0.80)
|
0.42
|
(0.28, 0.64)
|
< 0.001
|
|
Mean radial diffusivity, 10−3 mm2/s
|
1.08 ± 0.35
|
1.37 ± 0.33
|
0.74
|
(0.67–0.81)
|
0.40
|
(0.28, 0.59)
|
< 0.001
|
|
Mean FA‡
|
0.28 ± 0.15
|
0.23 ± 0.13
|
0.61
|
(0.53–0.68)
|
1.45
|
(1.11, 1.91)
|
0.007
|
|
Mean λ1 − λ3‡, 10−3 mm2/s
|
0.69 ± 0.46
|
0.69 ± 0.40
|
0.52
|
(0.44–0.60)
|
0.96
|
(0.74, 1.25)
|
0.77
|
