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Fig. 5 | Breast Cancer Research

Fig. 5

From: Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer

Fig. 5

CTC clusters from mice bearing MDA-MB-231 xenograft tumors. CTC clusters were isolated using the Vortex platform and stained with DAPI, human cytokeratin (CK), human vimentin (VIM), and mouse CD45. CTCs within clusters were identified as cells positive for DAPI, cytokeratin, and/or vimentin and negative for CD45. Note the heterogeneous composition of cells within some clusters

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