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Fig. 2 | Breast Cancer Research

Fig. 2

From: Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer

Fig. 2

Blood collection site for CTC isolation from mouse blood using a MDA-MB-231 TNBC xenograft model. a Workflow schematic. b, c Tumor growth and numbers of CTCs, including counts of single CTCs in panel b and CTC clusters in panel c; blood was obtained by cardiac puncture in sets of three mice weekly after implantation. d Saphenous vein collection provided less CTCs despite relatively similar tumor growth over time. e CK+ epithelial cells were identified in retroorbital blood collected from control mice without tumors

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