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Table 2 Breast cancer treatment initiation within 1 year of diagnosis in the ABC-DO cohort: percentage untreated and odds ratios for initiating treatment associated with socio-demographic, comorbidities and stage at diagnosis

From: Inequities in breast cancer treatment in sub-Saharan Africa: findings from a prospective multi-country observational study

 

Women not treated

227 (17.2%)

Women treated

1098 (82.8%)

Odds ratios for initiating treatment within 12 months of diagnosis

Test for interaction with population group

N (row %), all sites combined

OR (95% CI)A

OR (95% CI)B

p

Stage at breast cancer diagnosis

    

0.408

 I and II

47 (10.4)

403 (89.6)

1

1

 

 III

101 (16.9)

496 (83.1)

0.86 (0.57 to 1.28)

0.96 (0.63 to 1.45)

 

 IV

41 (20.1)

163 (79.9)

0.60 (0.36 to 0.98)

0.63 (0.37 to 1.07)

 

 Unknown

38 (51.4)

36 (48.6)

0.26 (0.14 to 0.45)

0.26 (0.14 to 0.48)

 

Age at diagnosis

    

0.640

 < 40

64 (20.9)

243 (79.1)

0.70 (0.44 to 1.10)

0.68 (0.42 to 1.10)

 

 40–< 50

65 (17.4)

308 (82.6)

0.83 (0.53 to 1.30)

0.77 (0.48 to 1.23)

 

 50–< 60

46 (14.3)

276 (85.7)

1

1

 

 60–< 70

32 (16.2)

165 (83.8)

0.76 (0.44 to 1.30)

0.74 (0.42 to 1.31)

 

 ≥ 70

20 (15.8)

107 (84.2)

0.48 (0.25 to 0.93)

0.57 (0.29 to 1.16)

 

SEP

    

0.917

 Low

129 (21.5)

408 (78.5)

1

1

 

 Middle

56 (15.1)

382 (84.9)

1.20 (0.81 to 1.79)

1.17 (0.77 to 1.76)

 

 High

42 (11.8)

246 (88.2)

2.40 (1.56 to 3.69)

2.45 (1.53 to 3.90)

 

Employment

    

0.941

 Unskilled

172 (18.8)

751 (81.2)

0.70 (0.48 to 1.02)

0.83 (0.56 to 1.23)

 

 Skilled

55 (13.8)

348 (86.2)

1

1

 

BMI

(kg/m2)

    

0.023

 < 18.5

9 (11.6)

124 (88.4)

1.58 (0.70 to 3.59)

1.83 (0.79 to 4.21)

 

 18.5–25

103 (20.4)

404 (89.6)

1

1

 

 25–30

67 (17.5)

315 (82.5)

1.09 (0.74 to 1.59)

0.96 (0.65 to 1.41)

 

 30+

35 (11.5)

269 (88.5)

1.76 (1.10 to 2.81)

1.53 (0.95 to 2.47)

 

Residential area

    

0.123

 Urban

112 (16.5)

569 (83.5)

1

1

 

 Rural

115 (17.9)

530 (82.1)

0.88 (0.61 to 1.25)

1.07 (0.73 to 1.56)

 

Breast cancer knowledge

   

0.286

 Yes

170 (15.8)

905 (84.2)

1

1

 

 No

57 (22.7)

194 (77.3)

0.80 (0.54 to 1.17)

0.81 (0.55 to 1.21)

 

Belief in traditional medicine

   

0.013

 Yes

80 (25.2)

238 (74.8)

0.63 (0.44 to 0.89)

0.67 (0.47 to 0.97)

 

 No

147 (14.6)

860 (83.4)

   

Belief in spiritual healing

   

0.004

 Yes

149 (17.4)

727 (82.6)

1.18 (0.83 to 1.68)

1.21 (0.84 to 1.21)

 

 No

78 (17.0)

371 (83.0)

1

  

HIV statusC

    

n.a.

 Negative

61 (16.1)

1143 (83.9)

1

1

 

 Positive

16 (32.0)

39 (68.0)

0.39 (0.19 to 0.79)

0.33 (0.16 to 0.70)

 
  1. BC breast cancer, BMI body mass index, CI confidence interval, OR odds ratio, SEP socio-economic position
  2. AOR adjusted for the ABC-DO population group, breast cancer stage at diagnosis and age at diagnosis
  3. BOR adjusted for the ABC-DO population group, breast cancer stage at diagnosis, age at diagnosis, SEP, BMI and residential area
  4. CLogistic regression models restricted to the Ugandan women (N = 430)