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Fig. 7 | Breast Cancer Research

Fig. 7

From: Dynamically decreased miR-671-5p expression is associated with oncogenic transformation and radiochemoresistance in breast cancer

Fig. 7

A schematic model for the dynamic regulation of miR-671-5p during the BC oncogenic transformation. miR-671-5p directly targets FOXM1. Downregulation of FOXM1 could (1) inhibit EMT-associated cell proliferation in DCIS (21NT) and IDC (21MT) cell lines, (2) inhibit EMT-associated invasion in ADH (21PT), DCIS (21NT), and IDC (21MT) cell lines, and (3) improve DNA repair capability-associated UV sensitivity in all stages during the oncogenic transformation of BC

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