Table 2 Multivariable fractional polynomial functions and logarithm hazard ratios for breast cancer-specific survival using all variables
From: Development of a prediction model for breast cancer based on the national cancer registry in Taiwan
Variables | Function | logHR | P value |
|---|---|---|---|
Continuous variables | |||
Age1 | (age/100)−0.5 | − 10.87 | 0.0035 |
Age2 | (age/100)−0.5 × log(age/100) | 8.968 | < 0.001 |
Tumor size, mm | log(size/10) | 0.7678 | < 0.001 |
Node-positive ratio | ((ratio + 0.1)/0.1)0.5 | 0.5339 | < 0.001 |
Categorical variables | |||
Chemotherapy | |||
Without | – | – | – |
With | – | − 0.4147 | < 0.001 |
Radiotherapy | |||
Without | – | – | – |
With | – | − 0.3203 | < 0.001 |
Grade | |||
1 | – | – | – |
2 | – | 0.4795 | 0.015 |
3 | – | 0.818 | < 0.001 |
Subtype | |||
Luminal-like | – | – | – |
HER2 | – | 0.1806 | 0.22 |
Triple negative | – | 0.6457 | < 0.001 |
Pathological stage | |||
1 | – | – | – |
2 | – | 0.5311 | < 0.001 |
3 | – | 1.134 | < 0.001 |
4 | – | 2.172 | < 0.001 |
Targeted therapy | |||
Without | – | – | – |
With | – | − 0.4687 | 0.001 |
Hormone/steroid therapy | |||
Without | – | – | – |
With | – | − 0.8397 | < 0.001 |
Lymph vessel or vascular invasion (LVI) | |||
No | – | – | – |
Yes | – | 0.3321 | < 0.001 |