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Fig. 6 | Breast Cancer Research

Fig. 6

From: Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers

Fig. 6

Gains in 18q determine recurrence and overexpression of SMAD2. a SMAD4 copy number in recurrent vs. non-recurrent cancers by ANOVA. Red and black dots represent gains and normal/loss, respectively (n = 46; Student’s t test). b Kaplan-Meier disease-free and overall survival of SMAD4 gains versus all others (n = 51, 19 vs. 32; DFS: HR = 2.30 (1.08–4.87); p = 0.01; OS: non-significant). c SMAD2 overexpression association with 18q gains by ANOVA (n = 51)

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