Fig. 4
From: Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers
Graduated p53 inactivation and outcome in BRE09-146. a Lollipop plot of TP53 mutations in BRE09-146. b Kaplan-Meier disease-free and overall survival analysis of TNBCs with < 2 copies vs. ≥ 2 copies of TP53 (n = 75, 53 vs. 22; DFS: HR = 2.07 (1.03–4.17), p = 0.02; OS: HR = 2.07 (0.96–4.48); p = 0.03). c Three-way Kaplan-Meier analysis of disease-free and overall survival analysis comparing outcomes based upon risk stratification predicted by the degree of genomic loss of TP53 (14 vs. 21 vs. 40; DFS: p = 0.02; OS: p = 0.02)