Table 2 Selected hotspot mutations in MPA/DMBA-induced tumors
Sample | Gene | Amino acid change |
|---|---|---|
S176_14_2 | Ctnnb1 | Asp32Asn |
S416_15_2 | Ctnnb1 | Thr41Ile |
S187_14_1 | Hras | Gln61Leu |
S412_15_2 | Hras | Gln61Leu |
S159_14_8 | Kras | Gly12Cys |
S160_14_2 | Kras | Gly12Cys |
S176_14_2 | Kras | Gly13Arg |
S189_14_2 | Kras | Gln61His |
S153_14_2 | Nras | Gln61Leu |
S416_15_9 | Nras | Gln61Leu |
S187_14_1 | Pik3ca | His1047Arg |
S132_14_5 | Trp53 | His211Pro |
S153_14_2 | Trp53 | Lys129Met |
S400_15_2 | Trp53 | Gln141Pro |
S400_15_2 | Trp53 | His211Pro |