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Fig. 5 | Breast Cancer Research

Fig. 5

From: Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers

Fig. 5

Gene expression characteristics of claudin-low-like MPA/DMBA-induced tumors and human claudin-low breast cancers. a MPA/DMBA-induced claudin-low-like tumors recapitulated the gene expression characteristics of the claudin-low subtype as evidenced by the expression levels of relevant gene signatures. p values are calculated for the claudin-low-like tumors versus tumors in the mixed cluster. b Cd274 and Ptgs2 are expressed at significantly higher levels in the claudin-low-like tumors than in the mixed cluster tumors. c Claudin-low is the breast cancer subtype with the highest expression of CD274 and PTGS2

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