Table 1 Patient characteristics
Clinicopathologic characteristics of patients in the training and validation cohorts | |||
|---|---|---|---|
Baseline characteristic | Training cohort (N = 159) | Validation cohort (N = 185) | Difference (p value) |
Patient age | |||
 Median age (range), years | 57 (30–83) | 59 (36–77) | 0.30 |
 Age < 50, n (%) | 26 (16.3) | 23 (12.4) | |
 Age ≥ 50, n (%) | 133 (83.7) | 162 (87.6) | |
Menopausal status, n (%) | |||
 Pre | 31 (19.5) | 29 (15.7) | 0.35 |
 Post | 128 (80.5) | 156 (84.3) | |
Presentation, n (%) | |||
 Screening | 85 (53.5) | 120 (64.9) | 0.03 |
 Symptomatic | 74 (46.5) | 65 (35.1) | |
Comedo necrosis, n (%) | |||
 No | 60 (37.7) | 34 (18.4) | < .0001 |
 Yes | 99 (62.3) | 151 (81.6) | |
Radiation, n (%) | |||
 No | 117 (73.6) | 145 (78.4) | 0.30 |
 Yes | 42 (26.4) | 40 (21.6) | |
Grade, n (%) | |||
 1 | 25 (15.8) | 0 (0.0) | < .0001 |
 2 | 24 (15.2) | 0 (0.0) | |
 3 | 109 (69.0) | 185 (100.0) | |
Margins, n (%) | |||
 Negative | 154 (97.5) | 183 (98.9) | 0.31 |
 Positive | 4 (2.5) | 2 (1.1) | |
Tumor size | |||
 Median tumor size (range), cm | 1.7 (0.1–14.5) | 1.7 (0.2–12.0) | 0.74 |
 Size < 2.0, n (%) | 88 (56.4) | 101 (55.6) | |
 Size ≥ 2.5, n (%) | 68 (43.6) | 84 (45.4) | |
Survival status, n (%) | |||
 Alive | 109 (68.6) | 159 (86.0) | 0.00 |
 Dead | 50 (31.4) | 26 (14.0) | |
10-year recurrence status, n (%) | |||
 Recurrence free | 128 (80.5) | 159 (85.9) | 0.18 |
 Recurred | 31 (19.5) | 26 (14.1) | |