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Table 1 Summary of patient characteristics for the NEO study and I-SPY validation set

From: On-treatment biomarkers can improve prediction of response to neoadjuvant chemotherapy in breast cancer

Characteristics NEO cohort (50) NEO cohort PT-TM pairs (23) p value I-SPY 1 PT-T2 pairs (36) p value
Median age at diagnosis 50.8 50.1 0.8 47  
Tumour grade    0.52   0.58
 1 0 (0%) 0 (0%)   1 (3%)  
 2 22 (44%) 12 (52%)   20 (55%)  
 3 28 (56%) 11 (48%)   15 (42%)  
Hormone receptor status    0.24   0.66
 Positive 23 (46%) 14 (61%)   24 (67%)  
 Negative 27 (54%) 9 (39%)   12 (33%)  
HER2 status    0.87   0.64
 Positive 10 (20%) 5 (22%)   6 (17%)  
 Negative 40 (80%) 18 (78%)   30 (83%)