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Fig. 4 | Breast Cancer Research

Fig. 4

From: Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization

Fig. 4

NNMT expression decreases apoptosis induced by ADM or PTX in BCs. Cells were exposed to various concentrations of ADM or PTX for 48 h, and the apoptosis was assessed by flow cytometry (n = 3) (**p < 0.01). The group with vector or NC served as the control group for each cell model. ac The scattergrams of the representative flow cytometry results. ei The quantification results of a, b, and c. a, d, e Apoptosis in the SK-BR-3 cell model. b, f, g Apoptosis in the MCF7 cell model. c, h, i Apoptosis in the MDA-MB-231 cell model

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