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Table 2 Median time to treatment failure on treatment regimen received immediately after TREnd, according to the absolute number of previous lines of treatment received. This takes into account previous endocrine therapy line(s) +/βˆ’ chemotherapy (TREnd allowed subjects to have a maximum of one previous line of chemotherapy for advanced disease prior to enrolment)

From: Clinical outcomes after palbociclib with or without endocrine therapy in postmenopausal women with hormone receptor positive and HER2-negative metastatic breast cancer enrolled in the TREnd trial

Number of previous lines of treatment received Patients (number) Recorded events (number) Median TTF (months) 95% CI
Two lines 51 47 3.73 3.39–5.07
Three lines 44 43 4.18 3.09–6.28
Four lines 10 9 3.85 2.20–NA
  1. TTF time to treatment failure, CI confidence interval, NA not assessable