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Table 1 Histo-scores (H-score, mean ± stdev) and p values from selected antibodies

From: Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer

Protein

Histo-score

Level of significance

MAS98.06

MAS98.12

p value

ALDH18A1

147 ± 25

23 ± 9

6e−06

cMYC

99 ± 52

159 ± 32

ns (0.06)

GLUD1

131 ± 35

86 ± 11

0.03

GLS1

210 ± 25

256 ± 43

ns (0.08)

GS

164 ± 25

168 ± 38

ns (0.85)

PYCR1

128 ± 24

90 ± 18

0.02

SLC1A5

132 ± 17

178 ± 6

4e−04

  1. Abbreviations: ALDH18A1 aldehyde dehydrogenase 18 family member A1, GLUD1 glutamate dehydrogenase 1, GLS1 glutaminase, GS glutamine synthetase, ns not significant, PYCR1 pyrroline-5-carboxylate reductase 1, and SLC1A5 solute carrier family 1 member 5 (glutamine transporter)
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Breast Cancer Research

ISSN: 1465-542X

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