ISGF3 | U-ISGF3 | GAS |
---|
MX1/2 | IRF9 | MX1/2 | IFITM1 |
IFITM1 | IRF4 | IFITM1 | STAT4 |
PLSCR1 | cGAS | PLSCR1 | IRF1 |
OAS1/2/3 | STAT1 | OAS1/2/3 | IRF8 |
SOCS | STAT2 | IRF7 | IDO |
USP18 | NOS2 | STAT1 | NOS2 |
ISG15 | Â | IFI27 | PDGFRA |
IRF3 | Â | IFI44 | KRT14 |
IRF7 | Â | Â | IRF2 |
- ISGF3 (interferon-stimulated gene factor 3), consists of phosphorylated STAT1 and STAT2 dimers bound to IRF9; U-ISGF3 (unphosphorylated interferon-stimulated gene factor 3), consists of a dimer of unphosphorylated STAT proteins bound to IRF9; GAS (gamma activated sequence), consists of phosphorylated STAT1 dimers