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Table 2 Mean relative telomere length by characteristics of women, the Singapore Chinese Health Study

From: Association between prediagnostic leukocyte telomere length and breast cancer risk: the Singapore Chinese Health Study

Variables Age at blood draw Number Telomere length (95% CI) P 1
Age at sample collection, years
 45 to < 55 52.5 2452 1.11 (1.10, 1.12) < 0.0001
 55 to < 60 56.8 3528 1.09 (1.08, 1.09)
 60 to < 65 62.0 3173 1.04 (1.03, 1.05)
 ≥ 65 70.9 5152 0.98 (0.97, 0.99)
Body mass index, kg/m2
 < 18.5 63.6 1016 1.04 (1.02, 1.05) 0.21
 18.5 to < 23.0 61.8 5859 1.05 (1.04, 1.05)
 23.0 to < 27.5 62.6 5716 1.05 (1.04, 1.05)
 ≥ 27.5 62.3 1714 1.04 (1.03, 1.05)
Level of education
 No formal education 66.4 4580 1.05 (1.04, 1.06) 0.16
 Primary school 61.6 6034 1.04 (1.04, 1.05)
 Secondary school and above 58.3 3691 1.04 (1.03, 1.05)
Dialect group
 Cantonese 62.5 7519 1.04 (1.04, 1.05) 0.08
 Hokkien 62.0 6786 1.05 (1.04, 1.05)
Alcohol consumption, drinks/week
 None 62.5 12,788 1.04 (1.04, 1.05) 0.41
 < 7 60.6 1331 1.05 (1.04, 1.06)
 ≥ 7 62.0 186 1.06 (1.03, 1.09)
Physical activity (weekly)
 No 62.4 10,421 1.04 (1.04, 1.05) 0.71
 Yes 61.9 3884 1.04 (1.04, 1.05)
Smoking status
 Never 61.8 13,053 1.04 (1.04, 1.05) 0.87
 Former 68.3 570 1.04 (1.02, 1.06)
 Current 66.7 682 1.04 (1.03, 1.06)
Age when period became regular
 < 13 59.1 1988 1.04 (1.04, 1.05) 0.77
 13–14 61.5 5152 1.04 (1.04, 1.05)
 15–16 63.5 4578 1.05 (1.04, 1.05)
 ≥ 17 64.7 2087 1.05 (1.04, 1.05)
 Never regular 61.7 500 1.06 (1.04, 1.08)
Age at first live birth
 < 20.0 65.6 2420 1.05 (1.04, 1.06) 0.42
 21.0–25.0 62.5 5357 1.04 (1.04, 1.05)
 26.0–30.0 60.8 3962 1.04 (1.03, 1.05)
 ≥ 31 61.0 1526 1.05 (1.04, 1.06)
 Nulliparous 61.3 1040 1.04 (1.03, 1.06)
Number of live births
 0 61.2 1027 1.04 (1.03, 1.05) 0.07
 1–2 59.3 4327 1.04 (1.03, 1.05)
 3–4 61.3 5748 1.04 (1.04, 1.05)
 ≥ 5 68.6 3158 1.05 (1.05, 1.06)
Menopausal status
 Premenopausal 52.6 955 1.03 (1.02, 1.05) 0.09
 Postmenopausal 63.0 13,350 1.05 (1.04, 1.05)
Age at menopause
 ≤ 49 69.4 2425 1.05 (1.04, 1.06) 0.97
 50–54 68.8 3376 1.04 (1.04, 1.05)
 ≥ 55 57.7 8504 1.04 (1.04, 1.05)
Family history of breast cancer
 No 62.3 14,065 1.04 (1.04, 1.05) 0.20
 Yes 60.6 240 1.06 (1.03, 1.09)
Use of hormone therapy
 Never 63.0 11,890 1.06 (1.05, 1.08) 0.82
 Ever 59.6 1602 1.04 (1.03, 1.05)
 Current 57.4 813 1.04 (1.04, 1.05)
Use of oral contraceptive
 Never 63.2 9888 1.05 (1.04, 1.05) 0.23
 Former/current 60.2 4417 1.04 (1.03, 1.05)
Sleeping hours
 ≤ 6 h 63.2 4871 1.05 (1.04, 1.05) 0.04
 7–8 h 61.8 8503 1.04 (1.04, 1.05)
 ≥ 8 h 62.4 931 1.03 (1.01, 1.04)
  1. 1Values are least-square means (95% confidence intervals), and P values were derived from ANCOVA with adjustment for age at blood collection and dialect group