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Fig. 5 | Breast Cancer Research

Fig. 5

From: The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

Fig. 5

MIR2052HG regulates LMTK3 transcription by facilitating EGR1 recruitment to the LMTK3 promoter. a Dual RNA-DNA-FISH demonstrates that MIR2052HG transcripts (green signal) are localized onto the LMTK3 gene locus (red signal) in MCF7/AC1 and CAMA-1 cells. b, c EGR1 antibody immunoprecipitates MIR2052HG, but not negative control lncRNA LOC102724785 in MCF7/AC1 (b) and CAMA-1 (c) cells. Error bars represent SEM of two independent experiments in triplicate; **p < 0.01

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