Genomic signature of parity in the breast of premenopausal women

Breast Cancer Research

Table 5 Correlation of real-time RT-PCR and microarray results

Genes	Affymetrix probeset	TaqMan Assay ID	Microarray		Real time		ICC	Spearman correlation
Genes	Affymetrix probeset	TaqMan Assay ID	FC	P	FC	P	ICC	Spearman correlation
WIF1	204712_at	Hs00183662_m1	0.39	0.055	0.32	0.034	0.92	0.94
FOXQ1	227475_at	Hs00536425_s1	0.64	0.020	0.70	0.218	0.64	0.69
FZD8	227405_s_at	Hs00259040_s1	1.3	0.003	1.17	0.188	0.43	0.42
SDC1	201286_at	Hs00896423_m1	1.48	0.014	1.19	0.456	0.73	0.62
EAF2	219551_at	Hs00218407_m1	1.36	0.008	1.24	0.059	0.35	0.41
BHLHE22	228636_at	Hs01084964_s1	1.24	0.078	1.35	0.022	0.41	0.53
APOBEC3G	204205_at	Hs00222415_m1	1.44	0.000	1.44	0.001	0.39	0.48
DSC3	206033_s_at	Hs00170032_m1	1.70	0.002	1.45	0.063	0.64	0.51
KRT5	201820_at	Hs00361185_m1	1.51	0.012	1.54	0.062	0.64	0.71
EGR3	206115_at	Hs00231780_m1	1.71	0.026	1.57	0.072	0.76	0.70
RASGRP1	205590_at	Hs00996727_m1	1.61	0.002	1.71	0.002	0.66	0.74

Correlation of real-time RT-PCR and microarray results were calculated using the 20 parous vs. 17 nulliparous samples, for whom enough RNA material was still available. FC mean fold change, P batch-adjusted p value, ICC intraclass correlation coefficient

ISSN: 1465-542X