Breast cancer risk prediction in women aged 35–50 years: impact of including sex hormone concentrations in the Gail model

Breast Cancer Research

Table 4 Absolute risk reclassification upon adding AMH and testosterone to the Gail model

		Gail + AMH + testosterone 5-year risk		Moved up (%)	Moved down (%)
Reclassification in cases		< 1%	≥ 1%
Gail 5-year risk	< 1%	588	163
	≥ 1%	143	868
				9.3%	8.1%
Reclassification in controls		< 1%	≥ 1%
Gail 5-year risk	< 1%	708	165
	≥ 1%	196	821
				8.7%	10.4%