Table 1 List of the drugs that were most effective in inhibiting EMT in the mesenchymal MDA-MB 231 reporter cells and their reported targets
Drug | Target | |
|---|---|---|
1 | TSU-68 (orantinib) | VEGFR, PDGFR, FGFR |
2 | Rocilinostat (ACY-1215) | HDAC |
3 | Trichostatin A (TSA) | HDAC |
4 | CUDC-101 | HDAC, HER2, EGFR |
5 | PD168393 | EGFR |
6 | SCH79797 | Par1 antagonist |
7 | CP-673451 | PDGFR |
8 | Panobinostat (LBH589) | HDAC |
9 | BIO | GSK3 |
10 | Cabozantinib malate | VEGFR, Axl |
11 | GW9662 | PPAR |