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Fig. 5 | Breast Cancer Research

Fig. 5

From: GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

Fig. 5

GSK3β is significantly upregulated in breast cancer. a GSK3β is significantly upregulated at the transcript levels in breast cancer tissues as compared to normal tissues in the Ma, Richardson, and TCGA datasets. b The KM plots generated using KMPlotter showed that higher expression of GSK3β correlates with worse survival only in TNBCs but not in the case of ER/PR-positive and HER2-positive breast cancers. GSK3β is the only signaling molecule in the Wnt signaling pathway that has a high hazard ratio and a significant p value. c Hazard ratios and the p values for several of the major players of the Wnt signaling pathway were generated and plotted for TNBC patients

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