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Table 3 Cox proportional hazards models for RFS, DMFS and OS. All significant clinicopathological variables were included in a multivariate Cox proportional hazards model. Distant disease at diagnosis, nodal status and sTIL infiltration are significantly associated with OS. In the group with initially localised disease, nodal disease was significantly associated with OS and both pCR after NACT and HR status were associated with RFS. *Significant P values in italic

From: Infiltrating stromal immune cells in inflammatory breast cancer are associated with an improved outcome and increased PD-L1 expression

Parameter Hazard ratio Lower 95% CI Higher 95% CI P value*
Cox proportional hazards model for OS in the total population
sTIL (> 10%) 0.465 0.266 0.811 0.006
cN stage 1.635 1.137 2.353 0.008
cM stage 3.060 1.794 5.219 < 0.001
HR status 0.631 0.357 1.114 0.11
Cox proportional hazards model for RFS (initially localised disease)
cN stage 1.354 0.876 2.093 0.17
HR status 0.471 0.249 0.889 0.02
Taxane NACT 0.934 0.424 2.055 0.86
pCR 0.406 0.166 0.992 0.05
Cox proportional hazards model for DMFS (initially localised disease)
cN stage 1.530 0.981 2.39 0.06
HR status 0.564 0.295 1.08 0.08
Taxane NACT 0.771 0.348 1.71 0.52
pCR 0.391 0.149 1.03 0.06
Cox proportional hazards model for OS (initially localised disease)
cN stage 1.652 1.020 2.674 0.04
HR status 0.453 0.224 0.918 0.03
Taxane NACT 0.672 0.296 1.524 0.34
pCR 0.368 0.126 1.075 0.07