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Fig. 1 | Breast Cancer Research

Fig. 1

From: MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors

Fig. 1

a Representative pictures of single mammospheres of the cell lines MCF7, BT474, and SUM159 used for profiling the whole miRNome. b–c Heat map and corresponding tables with fold changes of the top 10 down- and upregulated miRNAs in mammospheres compared to adherent growing cells. d A significantly lower expression level (4.6-fold downregulation) for miR-1287-5p was found in cancer tissue compared to corresponding normal tissue. e Low levels of miR-1287 were a negative prognostic factor for survival in an independent external large cohort of 1262 breast cancer patients (HR = hazard ratio)

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Breast Cancer Research

ISSN: 1465-542X

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