Table 3 Diagnostic performance of preoperative CE-MRI in different histologic and biologic tumor subtypes
Percentage (95% CI) | Ductal | Lobular | Others | P value* | HR+ | HR- | P value* |
|---|---|---|---|---|---|---|---|
pCR rate: | 33% | 12% | 10% | 18% | 40% | ||
Sensitivity | 76% (64–86%) | 0% (0–76%) | 100% (11–100%) | 0.120 | 77% (55–92%) | 73% (59–85%) | 0.777 |
Specificity | 70% (62–78%) | 67% (35–85%) | 58% (32–77%) | 0.488 | 65% (55–76%) | 69% (57–79%) | 0.631 |
PPV | 56% (45–66%) | 0% (0–47%) | 20% (2–51%) | 0.003 | 33% (20–47%) | 61% (47–73%) | 0.004 |
NPV | 85% (77–91%) | 83% (46–95%) | 100% (65–100%) | 0.536 | 93% (84–97%) | 80% (68–89%) | 0.040 |
Accuracy | 72% (65–78%) | 59% (33–81%) | 62% (37–81%) | 0.024 | 67% (58–75%) | 71% (62–78%) | 0.004 |