Skip to main content

Table 3 Gene Ontology: Biological Processes for genes associated with hypermethylated gene regions

From: Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier

Accession Description Number of genes Number of input genes Expected ratio Observed ratio P value Bonferroni P value
GO:0071103 DNA conformation change 248 10 1.39 7.20 1.24E-06 0.011
GO:0006323 DNA packaging 165 8 0.92 8.66 3.95E-06 0.017
GO:0031497 Chromatin assembly 128 7 0.72 9.77 7.44E-06 0.021
GO:0065004 Protein-DNA complex assembly 197 8 1.10 7.26 1.45E-05 0.031
GO:0006333 Chromatin assembly or disassembly 153 7 0.86 8.17 2.38E-05 0.041
GO:0006334 Nucleosome assembly 111 6 0.62 9.66 3.68E-05 0.045
GO:0071824 Protein-DNA complex subunit organization 224 8 1.25 6.38 3.65E-05 0.045
  1. The complete list of pathways can be found in Additional file 1: Table S6A