Data set (n) | Percentage ER positivitya | Percentage Predicted BRCA1-like | Purpose | Data types analyzed | Accession (if applicable) | Refs. |
---|---|---|---|---|---|---|
Joosse et al. (74) | 42.9 (27/63) | 47.3 (35/74) | BRCA1-like classifier training | Copy number | GSE9021, GSE9114 | |
BRCAx (106) | 70.7 (41/58) | 19.8 (21/106) | BRCA1-like classifier validation | Copy number | GSE18626 | [33] |
CCLE breast cancer cell lines (10) | 10.0 (1/10) | 60.0 (6/10) | BRCA1-like classifier experimental validation | Copy number, MLPA | Additional file 1: Table S1; portals.broadinstitute.org/ccle | |
TCGA breast cancer (957) | 77.1 (704/913) | 32.2 (308/957) | BRCA1-like differential analyses | Copy number, mutation, gene expression, DNA methylation, clinical | ||
METABRIC (1968) | 76.3 (1501/1968) | 17.4 (343/1968) | BRCA1-like differential analyses | Copy number, gene expression, clinical |