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Fig. 3 | Breast Cancer Research

Fig. 3

From: Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier

Fig. 3

Molecular characteristics of support vector machine (SVM) BRCA1-like hormone-receptor-positive tumors in The Cancer Genome Atlas (TCGA). Comparison of whole exome sequencing-based mutation rates per mega base-pair (Mb) (a) and Somatic Mutational Signature 3 related with HR-deficiency (b), and Ki-67 (MKI67) gene expression as a surrogate marker for cellular proliferation (c). Variations in the number of tumors were due to data availability (see “Materials and methods”). *P < 0.05, **P < 0.01, ***P < 0.001

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