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Table 2 Mammographic density measurements for cases and controls, by mode of detection (screen-detected or interval cancer)

From: Predicting interval and screen-detected breast cancers from mammographic density defined by different brightness thresholds

  Interval cancer Screen-detected cancer
Cases (n = 168)
Mean (SD)
Controls (n = 498)
Mean (SD)
P a Cases (n = 422)
Mean (SD)
Controls (n = 1197)
Mean (SD)
P a
Cumulus
 Dense area (cm2) 25 (13) 19 (11) < 0.001 21 (13) 19 (12) 0.001
 Non-dense area (cm2) 110 (54) 126 (56) 0.001 132 (59) 127 (55) 0.2
 Percent dense area 21 (11) 15 (9) < 0.001 16 (10) 14 (9) 0.01
 Total area (cm2) 135 (56) 145 (56) 0.04 153 (58) 146 (55) 0.04
Altocumulus
 Dense area (cm2) 12 (8) 9 (7) < 0.001 10 (7) 9 (8) 0.01
 Non-dense area (cm2) 124 (57) 137 (57) 0.008 144 (59) 138 (55) 0.09
 Percent dense area 11 (8) 7 (6) < 0.001 7 (6) 7 (6) 0.04
 Total area (cm2) 136 (57) 146 (57) 0.05 154 (59) 147 (55) 0.04
Cirrocumulus
 Dense area (cm2) 6.8 (6.2) 4.2 (4.6) < 0.001 4.8 (5.3) 3.9 (4.9) 0.002
 Non-dense area (cm2) 129 (55) 141 (56) 0.01 148 (58) 142 (55) 0.09
 Percent dense area 6.0 (5) 3.0 (4) < 0.001 4.0 (4) 3.0 (3) 0.003
 Total area (cm2) 135 (56) 145 (56) 0.05 153 (58) 146 (55) 0.05
  1. SD standard deviation
  2. aP indicates significance of differences between cases and matched controls based on conditional logistic regression