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Table 4 Self-reported change in neurotoxicity scores by tertiles of monthly servingsa of meats and other foods during treatment (FACT/GOG-Ntx subscale) (n = 900)

From: Associations between self-reported diet during treatment and chemotherapy-induced peripheral neuropathy in a cooperative group trial (S0221)

Food group

Total

< 10%a

10–30%b

> 30%b

p valuec

Protein

 Fish

    

0.98

  ≤ 1.5

320 (35.6)

101 (35.9)

110 (36.0)

109 (34.8)

 

  1.6–5.0

287 (31.9)

91 (32.4)

98 (32.0)

98 (31.3)

 

  > 5.0

293 (32.6)

89 (31.7)

98 (32.0)

106 (33.9)

 

 Poultry

    

0.90

   ≤ 2.0

306 (34.0)

93 (33.1)

104 (34.0)

109 (34.8)

 

  2.1–4.0

296 (32.9)

89 (31.7)

105 (34.3)

102 (32.6)

 

  > 4.0

298 (33.1)

99 (35.2)

97 (31.7)

102 (32.6)

 

 Red meats

    

0.98

   ≤ 5.0

319 (35.4)

97 (34.5)

111 (36.3)

111 (35.5)

 

  5.1–12.0

281 (31.2)

91 (32.3)

92 (30.1)

98 (31.3)

 

  > 12.0

300 (33.3)

93 (33.1)

103 (33.7)

104 (33.2)

 

 Processed meat

    

0.87

   ≤ 3.3

306 (34.0)

95 (33.8)

102 (33.3)

109 (34.8)

 

  3.4–8.8

294 (32.7)

89 (31.7)

107 (35.0)

98 (31.3)

 

  > 8.8

300 (33.3)

97 (34.5)

97 (31.7)

106 (33.9)

 

 Other proteins

    

0.47

   ≤ 6.0

311 (34.6)

97 (34.5)

98 (32.0)

116 (37.1)

 

  6.1–15.3

296 (32.9)

85 (30.3)

107 (35.0)

104 (33.3)

 

  > 15.3

293 (32.6)

99 (35.2)

101 (33.0)

93 (29.7)

 

Other foods

 Dairy

    

0.31

  ≤ 16.3

300 (33.3)

89 (31.7)

99 (32.4)

112 (35.8)

 

  16.3–39.5

300 (33.3)

87 (31.0)

113 (36.9)

100 (32.0)

 

  > 39.5

300 (33.3)

105 (37.4)

94 (30.7)

101 (32.3)

 

 Grains

    

0.01

  ≤ 27.5

301 (33.4)

78 (27.8)

97 (31.7)

126 (40.3)

 

  27.6–48.5

299 (33.2)

93 (33.1)

109 (35.6)

97 (31.0)

 

  > 48.5

300 (33.3)

110 (39.2)

100 (32.7)

90 (28.8)

 

 Sweets

    

0.31

  ≤ 15.5

305 (33.9)

96 (34.2)

93 (30.4)

116 (37.1)

 

  15.6–35.0

296 (32.9)

98 (34.9)

99 (32.4)

99 (31.6)

 

  > 35.0

299 (33.2)

87 (30.96)

114 (37.3)

98 (31.3)

 

 Fried foods

    

0.47

  ≤ 2.0

309 (34.3)

86 (30.6)

112 (36.6)

111 (35.5)

 

  2.1–5.3

302 (33.6)

105 (37.4)

97 (31.7)

100 (32.0)

 

  > 5.3

289 (32.1)

90 (32.0)

97 (31.7)

102 (32.6)

 

 Added fats

    

0.41

  ≤ 17.3

303 (33.7)

89 (31.7)

98 (32.0)

116 (37.1)

 

  17.3–34.0

299 (33.2)

103 (36.7)

101 (33.0)

95 (30.4)

 

  > 34.0

298 (33.1)

89 (31.7)

107 (35.0)

102 (32.6)

 

 Alcohol

    

0.009

  0.0

531 (59.0)

163 (58.0)

170 (55.6)

198 (63.3)

 

  0.1–2.0

191 (21.2)

58 (20.6)

84 (27.5)

49 (15.7)

 

  > 2.0

178 (19.8)

60 (21.4)

52 (17.0)

66 (21.1)

 
  1. Data presented as N (%)
  2. FACT/GOG-Ntx Functional Assessment of Cancer Treatment Gynecologic Oncology Group—Neurotoxicity
  3. aServing size based on United States Department of Agriculture portion sizes
  4. bPercent increase in neuropathy severity (based on self-reported score)
  5. cChi-square (α = 0.05)