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Table 4 Self-reported change in neurotoxicity scores by tertiles of monthly servingsa of meats and other foods during treatment (FACT/GOG-Ntx subscale) (n = 900)

From: Associations between self-reported diet during treatment and chemotherapy-induced peripheral neuropathy in a cooperative group trial (S0221)

Food group Total < 10%a 10–30%b > 30%b p valuec
Protein
 Fish      0.98
  ≤ 1.5 320 (35.6) 101 (35.9) 110 (36.0) 109 (34.8)  
  1.6–5.0 287 (31.9) 91 (32.4) 98 (32.0) 98 (31.3)  
  > 5.0 293 (32.6) 89 (31.7) 98 (32.0) 106 (33.9)  
 Poultry      0.90
   ≤ 2.0 306 (34.0) 93 (33.1) 104 (34.0) 109 (34.8)  
  2.1–4.0 296 (32.9) 89 (31.7) 105 (34.3) 102 (32.6)  
  > 4.0 298 (33.1) 99 (35.2) 97 (31.7) 102 (32.6)  
 Red meats      0.98
   ≤ 5.0 319 (35.4) 97 (34.5) 111 (36.3) 111 (35.5)  
  5.1–12.0 281 (31.2) 91 (32.3) 92 (30.1) 98 (31.3)  
  > 12.0 300 (33.3) 93 (33.1) 103 (33.7) 104 (33.2)  
 Processed meat      0.87
   ≤ 3.3 306 (34.0) 95 (33.8) 102 (33.3) 109 (34.8)  
  3.4–8.8 294 (32.7) 89 (31.7) 107 (35.0) 98 (31.3)  
  > 8.8 300 (33.3) 97 (34.5) 97 (31.7) 106 (33.9)  
 Other proteins      0.47
   ≤ 6.0 311 (34.6) 97 (34.5) 98 (32.0) 116 (37.1)  
  6.1–15.3 296 (32.9) 85 (30.3) 107 (35.0) 104 (33.3)  
  > 15.3 293 (32.6) 99 (35.2) 101 (33.0) 93 (29.7)  
Other foods
 Dairy      0.31
  ≤ 16.3 300 (33.3) 89 (31.7) 99 (32.4) 112 (35.8)  
  16.3–39.5 300 (33.3) 87 (31.0) 113 (36.9) 100 (32.0)  
  > 39.5 300 (33.3) 105 (37.4) 94 (30.7) 101 (32.3)  
 Grains      0.01
  ≤ 27.5 301 (33.4) 78 (27.8) 97 (31.7) 126 (40.3)  
  27.6–48.5 299 (33.2) 93 (33.1) 109 (35.6) 97 (31.0)  
  > 48.5 300 (33.3) 110 (39.2) 100 (32.7) 90 (28.8)  
 Sweets      0.31
  ≤ 15.5 305 (33.9) 96 (34.2) 93 (30.4) 116 (37.1)  
  15.6–35.0 296 (32.9) 98 (34.9) 99 (32.4) 99 (31.6)  
  > 35.0 299 (33.2) 87 (30.96) 114 (37.3) 98 (31.3)  
 Fried foods      0.47
  ≤ 2.0 309 (34.3) 86 (30.6) 112 (36.6) 111 (35.5)  
  2.1–5.3 302 (33.6) 105 (37.4) 97 (31.7) 100 (32.0)  
  > 5.3 289 (32.1) 90 (32.0) 97 (31.7) 102 (32.6)  
 Added fats      0.41
  ≤ 17.3 303 (33.7) 89 (31.7) 98 (32.0) 116 (37.1)  
  17.3–34.0 299 (33.2) 103 (36.7) 101 (33.0) 95 (30.4)  
  > 34.0 298 (33.1) 89 (31.7) 107 (35.0) 102 (32.6)  
 Alcohol      0.009
  0.0 531 (59.0) 163 (58.0) 170 (55.6) 198 (63.3)  
  0.1–2.0 191 (21.2) 58 (20.6) 84 (27.5) 49 (15.7)  
  > 2.0 178 (19.8) 60 (21.4) 52 (17.0) 66 (21.1)  
  1. Data presented as N (%)
  2. FACT/GOG-Ntx Functional Assessment of Cancer Treatment Gynecologic Oncology Group—Neurotoxicity
  3. aServing size based on United States Department of Agriculture portion sizes
  4. bPercent increase in neuropathy severity (based on self-reported score)
  5. cChi-square (α = 0.05)