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Fig. 7 | Breast Cancer Research

Fig. 7

From: Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics

Fig. 7

Scheme of metabolic network changes in the early and late stages of metastatic 4T1 breast cancer in mice. Early phase of metastasis is featured by a shift in L-arginine metabolism towards arginase linked with elevated polyamine biosynthesis, whereas the late phase of metastasis is characterized by energy metabolism reprogramming (‘Warburg effect’) and alterations in structural and signalling lipid profile in murine plasma

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Breast Cancer Research

ISSN: 1465-542X

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