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Fig. 9 | Breast Cancer Research

Fig. 9

From: The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer

Fig. 9

Aspirin and metformin overcome adaptive resistance of MCF10.AT1-R cells. a, b Images and quantification of the clonogenic survival assay, showing reduction in the number of colonies formed by MCF10.AT1-R cells treated with fluvastatin alone (flu (a))or fluvastatin (FV (b)) in combination with aspirin or metformin relative to vehicle control. Colonies ≥2 mm were scored and tabulated. Values represent average number of colonies ± SEM. Drug combinations are compared to fluvastatin alone and are significantly different; **p < 0.01, ***p < 0.001

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