Fig. 7From: The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancerAspirin and metformin overcome inherent resistance of MCF10.DCIS cells. a, b Images and quantification of a clonogenic survival assay showing reduction in the number of colonies formed by inherently resistant MCF10.DCIS cells treated with fluvastatin (Flu (a)) alone or fluvastatin (FV (b)) in combination with aspirin or metformin relative to vehicle control. Colonies ≥ 2 mm were scored and tabulated. Values represent average number of colonies ± SEM. Indicated drug combinations were significantly different from fluvastatin alone; ***p < 0.001Back to article page