Table 4 External validation of the estrogen receptor (ER)-specific risk prediction models and the Gail model in women from the Women’s Health Initiative (WHI) study
From: Risk prediction for estrogen receptor-specific breast cancers in two large prospective cohorts
ER-specific risk prediction models | ModelGail | ||
|---|---|---|---|
ModelER+ | ModelER− | ||
C-statistic (95% CI) | |||
Overall | 0.59 (0.58–0.60) | 0.53 (0.50–0.57) | 0.57 (0.56–0.59) |
By ER status | |||
ER+ | – | – | 0.58 (0.57–0.60) |
ER− | – | – | 0.53 (0.50–0.57) |
Ratio of observed–expected (95% CI) | 1.09 (1.03–1.14) | 0.94 (0.82–1.06) | 0.78 (0.73–0.82) |